In vitro supplementation with the porcine plasma product, betaGRO, stimulates activity of porcine fetal myoblasts and neonatal satellite cells in a divergent manner

Abstract

These findings suggest betaGRO� supplementation may enhance both myogenesis in utero and postnatal muscle hypertrophy. In utero, betaGRO� may help increase the muscle progenitor cell pool, thus possibly enhancing the establishment of muscle fiber number or the satellite cell pool. Postnatally, betaGRO� may stimulate increased protein synthesis by enhancing satellite cell fusion and signaling of the phosphatidylinositol 3-kinase pathway.